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MOTS-c

Login 0 press Enter to search Search results: No products found. Sale! MOTS-c $60.00 $190.00Price range: $60.00 through $190.00 MOTS-c is a 16-amino-acid peptide with the molecular formula C101H152N28O22S2 and a molecular weight of 2,174.6 g/mol (CAS 1627580-64-6). First described in 2015, MOTS-c is unusual because it is encoded by mitochondrial DNA rath

Published 2026-07-24GlycoMetrix
Abstract study of peptide signaling across a cell membrane

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MOTS-c

$60.00 $190.00Price range: $60.00 through $190.00

MOTS-c is a 16-amino-acid peptide with the molecular formula C101H152N28O22S2 and a molecular weight of 2,174.6 g/mol (CAS 1627580-64-6). First described in 2015, MOTS-c is unusual because it is encoded by mitochondrial DNA rather than nuclear DNA. It belongs to a class called mitochondrial-derived peptides (MDPs) short peptides encoded within the mitochondrial genome. Its sequence (MRWQEMGYIFYPRKLR) is found within the 12S rRNA gene of mitochondrial DNA, a region not previously known to produce peptides. MOTS-c is supplied as a white to off-white lyophilized powder, soluble in water, and should be stored refrigerated at 2-8 degrees C. This product is strictly for research purposes only.

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Description Additional information ✓ Third-Party Lab Tested

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Independent laboratory testing confirms purity and composition of this research peptide.

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Overview

MOTS-c is a 16-amino-acid peptide with the molecular formula C101H152N28O22S2 and a molecular weight of 2,174.6 g/mol. It was first described in 2015. What makes MOTS-c unusual among peptides is its origin: rather than being encoded by nuclear DNA (the DNA in the cell nucleus), it is encoded by the mitochondrial genome the small, separate set of DNA found inside mitochondria, the energy-producing compartments of cells. Its CAS number is 1627580-64-6.

MOTS-c belongs to a class of molecules called mitochondrial-derived peptides (MDPs), which are short peptides encoded within mitochondrial DNA. Only a handful of MDPs have been identified so far, making this a relatively new category in peptide science. The peptide’s amino acid sequence MRWQEMGYIFYPRKLR is encoded within the 12S rRNA gene of mitochondrial DNA, a region previously thought not to produce proteins. MOTS-c is supplied as a white to off-white lyophilized powder, soluble in water, and should be stored refrigerated at 36-46 degrees F (2-8 degrees C).

This product is strictly for research purposes only.

PubChem Reference: View compound profile on NIH PubChem

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C101H152N28O22S2

Weight: 2174.6 g/mol

CAS: 1627580-64-6

Sequence: 16 amino acids

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Water-soluble

Storage: Keep refrigerated 3646 °F (28 °C)

Stability: Stable when properly stored

Weight 0.08 lbs Dimensions 0.87 × 1.18 × 0.87 in Size

5mg, 10mg, 40mg

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